CONGRATULATIONS for 1st Runner-up Jizz A!
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Q&A and Hemato. Patho. Lab
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All credit goes to Amy.
Thanks for sharing on FB...this is meant for those who might not have been aware of it on FB or those who do not have FB. :)
Red blood cells
Look at the shape of the cells
- haemolytic HAS to be abnormal looking
- reticulocyte and target cells
- normocytic, macrocytic, microcytic
Look at the colour (-chromic)
MCV, MCH, MCHC
Types of haemolysis (test) :
Keep cells outside in tube (if haemolysis occurs, warm)
If not, put tube in fridge (if haemolysis occurs, cold)
If not, take out and leave it to stand (haemolysis, other type of cold)
Peripheral smear contains mature cells, but if nucleated cells/immature cells are present : Bone marrow hyperplasia
White blood cells
Decrease : leukopenia
Increase : Leukocytosis
If more than 11,000 : infection or malignancies
Shift to left : seeing cells above mature cells in the peripheral smear
Leukemoid reaction
Leukemia :
ALL and CLL
SK : what is in between A and C?
Us: B
SO ...
B
ALL : hence lymphoblast (smaller in size compared to myeloblast)
very dark, large nucleus, white vacuoles are present, more uniform in shape
very early childhood
CLL : ONLY lymphocytes, mature cells
smaller cells
very p;d, 80+
B
AML : hence myloblast
pale nucleus, irregular, auer ods present in the cytoplasm
any age
CML : mylocytes
spots in the cytoplasm
will see cell forms below band forms in the lineage
if see alot of myloblast, going into AML, mature cell count also increases, blast crisis
Platelets
Thrombocytosis
Thrombocytopenia
other minor ones
Teardrop cells : myeloprolif disorders
myodysplastic syndrome
Pancytopenia
----------------------------------------------------
Target cells : periphery is pale, center is thick, haemolysis, thalassemia
Macrocyte : B10 and B12 deficiency
Microcytic : Fe deficiency
HOW TO TELL WHEN LOOKING AT THE FLM?? compare to the nearest lymphocytes (WBC), same size/bigger (macro), super small (micro)
Haemolytic anemia : fragmented cells - burst cells, helmet cells
Haemorrhage : <1mm : petechiae
1mm - 1cm : purpura
Hematoma : large amount of blood that has undergone clot formation
Thalassemia : Pencil cells and mainly target cells are present
DO a bone marrow transplant
Bone marrow expands - bone expands = so when we take an xray, alot of thin hair like structure on the bone [crew cut appearance]
Reticulocyte in peripehral smear : excess bone marrow prolif
big, blueish, purple cells
If the FLM contains alot of empty spaces [vacuoles] = no cells = bone marrow has failed = pancytopenia
SPlenomegaly : severe destruction of cells - then will become small (autosplenectemy) // touch the abd, very painful (remember the robbers in arabia story yo!)
Hodgkin lymphoma : RS cells : large, double nuclei, lymphoblast
anisopoikilocytosis : variation in size and shape of the cell
Fe injection : gluteus muscle, SUPER deep ah! so that the Fe is absorbed - squueze the musc, inject till the whole needle is inside,press syringe - release hold on the musc abit,take out a lil bit of the syringe, press some more - release musc, take out the syringe alil bit, inject somemore
THERE'S NOTHING WRONG WITH INGESTING RUST YO! but shouldnt come into contact with epithelium
Barefoot : hookworm infestation - they be eats out blood, hence Fe deficiency anemia
-------------------------
If i got any facts wrong, let me know yea, i havent touched any HS notes :)
Look at the shape of the cells
- haemolytic HAS to be abnormal looking
- reticulocyte and target cells
- normocytic, macrocytic, microcytic
Look at the colour (-chromic)
MCV, MCH, MCHC
Types of haemolysis (test) :
Keep cells outside in tube (if haemolysis occurs, warm)
If not, put tube in fridge (if haemolysis occurs, cold)
If not, take out and leave it to stand (haemolysis, other type of cold)
Peripheral smear contains mature cells, but if nucleated cells/immature cells are present : Bone marrow hyperplasia
White blood cells
Decrease : leukopenia
Increase : Leukocytosis
If more than 11,000 : infection or malignancies
Shift to left : seeing cells above mature cells in the peripheral smear
Leukemoid reaction
Leukemia :
ALL and CLL
SK : what is in between A and C?
Us: B
SO ...
B
ALL : hence lymphoblast (smaller in size compared to myeloblast)
very dark, large nucleus, white vacuoles are present, more uniform in shape
very early childhood
CLL : ONLY lymphocytes, mature cells
smaller cells
very p;d, 80+
B
AML : hence myloblast
pale nucleus, irregular, auer ods present in the cytoplasm
any age
CML : mylocytes
spots in the cytoplasm
will see cell forms below band forms in the lineage
if see alot of myloblast, going into AML, mature cell count also increases, blast crisis
Platelets
Thrombocytosis
Thrombocytopenia
other minor ones
Teardrop cells : myeloprolif disorders
myodysplastic syndrome
Pancytopenia
--------------------------
Target cells : periphery is pale, center is thick, haemolysis, thalassemia
Macrocyte : B10 and B12 deficiency
Microcytic : Fe deficiency
HOW TO TELL WHEN LOOKING AT THE FLM?? compare to the nearest lymphocytes (WBC), same size/bigger (macro), super small (micro)
Haemolytic anemia : fragmented cells - burst cells, helmet cells
Haemorrhage : <1mm : petechiae
1mm - 1cm : purpura
Hematoma : large amount of blood that has undergone clot formation
Thalassemia : Pencil cells and mainly target cells are present
DO a bone marrow transplant
Bone marrow expands - bone expands = so when we take an xray, alot of thin hair like structure on the bone [crew cut appearance]
Reticulocyte in peripehral smear : excess bone marrow prolif
big, blueish, purple cells
If the FLM contains alot of empty spaces [vacuoles] = no cells = bone marrow has failed = pancytopenia
SPlenomegaly : severe destruction of cells - then will become small (autosplenectemy) // touch the abd, very painful (remember the robbers in arabia story yo!)
Hodgkin lymphoma : RS cells : large, double nuclei, lymphoblast
anisopoikilocytosis : variation in size and shape of the cell
Fe injection : gluteus muscle, SUPER deep ah! so that the Fe is absorbed - squueze the musc, inject till the whole needle is inside,press syringe - release hold on the musc abit,take out a lil bit of the syringe, press some more - release musc, take out the syringe alil bit, inject somemore
THERE'S NOTHING WRONG WITH INGESTING RUST YO! but shouldnt come into contact with epithelium
Barefoot : hookworm infestation - they be eats out blood, hence Fe deficiency anemia
-------------------------
If i got any facts wrong, let me know yea, i havent touched any HS notes :)
AML
Macrocytic anaemia ( and a few spherocytes)
Hypochromic microcytic anaemia ( and a few anisopoikilocytosis)
***
Undergraduate Talk
***
Please find invitation for the following lunch-time talk and kindly disseminate the info to your colleagues. This talk is opened to faculty and students.
Kindly compile the names of students who wish to attend.
---
"A lunch-time talk on Portfolio in Undergraduate Curricula by Dr Colin J Lumsden, Senior Teaching Fellow, University Of Manchester Medical School has been scheduled for Wednesday, 14 April 2010 from 12.00 -1.00pm in Auditorium 2, Level 4, Bukit Jalil. A synopsis of the talk is enclosed for your information.
This talk is opened to all faculty members and students."
For those of you who wish to attend, kindly confirm your participation. Please note that packed food will be provided after the talk.
Catherine
CtME
***
Undergraduate Talk
***
Please find invitation for the following lunch-time talk and kindly disseminate the info to your colleagues. This talk is opened to faculty and students.
Kindly compile the names of students who wish to attend.
---
"A lunch-time talk on Portfolio in Undergraduate Curricula by Dr Colin J Lumsden, Senior Teaching Fellow, University Of Manchester Medical School has been scheduled for Wednesday, 14 April 2010 from 12.00 -1.00pm in Auditorium 2, Level 4, Bukit Jalil. A synopsis of the talk is enclosed for your information.
This talk is opened to all faculty members and students."
For those of you who wish to attend, kindly confirm your participation. Please note that packed food will be provided after the talk.
Catherine
CtME
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